Although a number of studies in which patients experienced AKI have demonstrated the use of both urine and plasma NGAL are powerful independent predictors of AKI with a different proposed cut-offs for optimum utility of this test ranging from 10 to 550 ng/mL (4, 7, 9, 21), there is no clear guidance to offer the using of NGAL in AKI. Here, LCN2 is linked to acute kidney injury.