In FLX-treated [65], paroxetine-treated [31], and pilocarpine-treated animals [34], gene chip data reveals hippocampal upregulation of complement and MHC genes, and GFAP. Therefore, the changes in inflammation-related molecules in these mice with iDG are consistent with inflammatory features found in the brains of patients with schizophrenia and epilepsy. This evidence concerns the gene GFAP and schizophrenia.