Its production is induced by proinflammatory cytokines such as Interleukin-6 (IL-6), IL-8, and tumour necrosis factor alpha (TNF-α) and its levels have been positively correlated with weight loss, anorexia-cachexia syndrome, extent of disease, and recurrence in many cancer types including CRC [12]. This evidence concerns the gene CXCL8 and cancer.