Intriguingly, one eye described as normal (no diagnosed AMD) with the H/Y phenotype had intact photoreceptors (consistent with no loss of vision) but also had a drusen-like lesion on the fovea that contained small punctate deposits of CFH and Fib3 but again without the globular colocalization of the H/H eyes. The gene discussed is PCDHGA12; the disease is age-related macular degeneration.