The findings that Cdkn1A and Bax mRNA were higher in the thyroid of ThrbPV/PVNcor1ΔID/ΔID than ThrbPV/PVNcor1+/+ mice (Figure 5A) provided us with a tool to further investigate the mechanisms by which NCOR1 regulated thyroid carcinogenesis. This evidence concerns the gene CDKN1A and thyroiditis.