Linear multivariance regression analysis also showed a negative correlation of the mRNA expression of TRPC1, TRPC3, TRPC4 and TRPC6 to lung cancer differentiation grade with standardized β coefficient sequence of TRPC1 (−0.563)>TRPC4 (−0.360) >TRPC6 (+0.271) and TRPC3 (−0.057), respectively. The gene discussed is TRPC1; the disease is lung carcinoma.