MTAP and neoplasm: There were three distinct goals of these studies: 1) Strengthen the hypothesis that Mtap-loss plays a functional role in tumor formation; 2) Create a mouse model to study the effects of Mtap-loss on tumor formation that had a significantly shorter latency period than the original MtaplacZ/+ strain; and 3) Test the hypothesis that loss of Mtap might accelerate tumorigenesis in Eμ-myc mice by causing over expression of ODC.