The IDH1 gene is located on 2q33.3 and its mutation has been described in a very restricted number of human cancers including gliomas [3], [7], [8].The most common IDH1 mutation is a heterozygous missense mutation with a change of guanine to adenine at position 395 (G395A), leading to the replacement of arginine by histidine at codon132 (IDH1-R132H) at the enzymatic active site [10]. Here, IDH1 is linked to glioma.