This finding is interesting, as previous reports on the role of TLR2 or TLR9 in Mtb infections evidenced a more pronounced effect in later stages of infection, in terms of granuloma formation [24], [27], [29], [48], Th17 cell maintenance [24], [27], [29], [48] or Th1 cell differentiation [24], [27], [29], [48]. Here, TLR9 is linked to infection.