[8] This idea was further supported following the association between complement factor H polymorphisms and AMD, [9]–[12] and histological evidence has shown the presence of macrophages near many AMD lesions (areas of Bruch’s membrane degeneration, RPE atrophy and choroidal neovascularisation (CNV)). [13]–[18] In addition aqueous humour cytokine and chemokine concentrations are elevated in patients with AMD. [19], [20]. Here, CFH is linked to age-related macular degeneration.