Sequencing of candidate genes from breast cancer patients revealed that monoallelic germline mutations of DNA repair genes BRIP1 [MIM 605882], PALB2 [MIM 610335], ATM [MIM 607585], CHK2 [MIM 604373], RAD51C [MIM 602774] and RAD51D [MIM 602954] are associated with predisposition to hereditary breast cancer [3]–[5]. The gene discussed is BRIP1; the disease is breast carcinoma.