CD4 and tuberculosis: In the present study, we conducted a prospective analysis to estimate trajectories of activated T cell subsets and the profile of anti- and pro-inflammatory cytokines produced in a group of TB-HIV individuals, previously naïve for HAART, in TB-HIV patients during treatment for both diseases and the impact of the CD4 immunosuppression levels at baseline (below or above 200 cells/mm3) for the trends of such parameters.