PROK2 and neoplasm: Although this is thought to be mediated by Bv8 and Gcsf, a number of other inflammation genes such as Ptgs2 (log2 fold change = 1.54, p = 0.0001) and Il1b (log2 fold change = 1.23, p = 0.04) were up-regulated, which may also function to recruit inflammatory cells or bone marrow derived cells to the tumour following treatment.