In contrast to other in vitro studies, we included a long-segmental exon 11 deletion mutation, exon 11Val555_Leu576del, in our KIT mutant profile because segmental deletion is a more frequently detected KIT exon 11 mutation and associated with a worse clinical outcome after surgical resection than point mutation detected in advanced GIST [23]. This evidence concerns the gene KIT and gastrointestinal stromal tumor.