Taken together, it is reasonable to speculate that the present results strongly suggest that treatment of mice with quercetin cannot suppress NF-κB activation in Th2 type helper T cells induced by M. corti infection and that is causes the production of both IL-4 and IL-5 in vivo, resulting in eosinophilia and IgE hyperproduction in M. corti-infected, quercetin-treated mice. Here, IGHE is linked to Increased total eosinophil count.