CCL7 and injury: Increased monocyte chemotactic protein 3 (MCP-3, known as CCL7) expression associated with IL-6-dependent epigenetic modification at the MCP-3 promoter after nerve injury, mostly in spinal astrocytes, may serve to facilitate astrocyte-microglia interaction in the spinal cord and could play a critical role in the neuropathic pain-like state [63].