The suitability score is higher (1) the better the correlation between the copy-number profile of the cell line and the mean copy-number profile of HGSOC tumour samples; (2) the lower the frequency of non-synonymous mutations in protein-coding genes; (3) in the presence of a TP53 mutation; and (4) in the absence of mutations in the seven ‘non-HGSOC’ genes (see above) commonly altered in other ovarian cancer subtypes (Fig. 3, Supplementary Data S1). This evidence concerns the gene TP53 and ovarian cancer.