Strikingly, a higher mutation frequency in one of these ‘non-HGSOC’ oncogenes or tumour suppressors tends to coincide with a flat copy-number profile and wild-type TP53 (Fig. 1a), making these cell lines possible models of low-grade serous, endometrioid, clear cell or mucinous ovarian carcinoma17, 18, 19, 20, 21, 22, 23, 24, 25, 26. This evidence concerns the gene TP53 and neoplasm.