Morphological alterations were found in the livers of sedentary diabetic individuals, (DB/SD) probably caused by diabetes, such as the presence of smaller hepatocytes, suggesting the decrease of the cellular hepatic metabolism, once the glucose available in the blood could not be absorbed by the cell due to the decrease or absence of insulin, corroborating Remédio [33], who studied Wistar diabetic rats. The gene discussed is INS; the disease is diabetes mellitus.