The incidences of leukopenia and neutropenia in the anti-SSB antibody-positive group (63.16 and 53.58%, respectively) were significantly higher than those in the anti-SSB antibody-negative group (34.55 and 21.99%; χ2=4.749 and 6.418; P= 0.029 and 0.011, respectively). The gene discussed is SSB; the disease is neutropenia.