TEK and neoplasm: The final average tumor volumes were smaller in the carboplatin (332.99±73.91 mm3), Tie2-siRNA (392.78±81.74 mm3) and combined administration (70.11±22.09 mm3) groups than those in the G (909.05±73.42 mm3) or N (937.65±103.09 mm3) groups, and the differences were statistically significant (Fig. 1D).