NFATC2 and Dravet syndrome: Finally, the investigation of DSCR1/DYRK1A/NFAT genes, linked to the pathogenesis of DS in animal studies, confirmed increased protein levels of DSCR1 and DYRK1A and showed reduced levels of NFATc2 and decreased NFATc2 nuclear translocation upon calcium flows induction, adding new evidence to a transcriptional regulation deficit in DS.