Various studies have attempted to identify potential abnormalities in lymphocyte subsets and they reported that during relapses, the subsets of CD4+ and CD8+ T cells expanded and levels of their cytokines increased (interleukin-2, IL-4 and interferon-) in the patients with nephrotic syndrome but reports regarding these measurements are conflicting [1-4]. The gene discussed is CD4; the disease is nephrotic syndrome.