GGTLC1 and acute kidney injury: Early treatment with high dose rHuEPO compared with placebo following a rise in urine gamma glutamyl transpeptidase and alkaline phosphatase after cardiac surgery by Endre et al. [46] demonstrated no differences in changes in SCr from the baseline at 7 days, the incidence of CSA-AKI, duration of ICU and hospital stays, and rates of RRT and death.