To investigate this in more detail we first looked at CYCLON and MYC expression in a panel of BL (Raji, BL41, BL136) and DLBCL cell lines of both the GCB (B593, SUDHL4, HT) and ABC subtypes (OCI-LY3, OCI-LY10) (Fig 5A). The gene discussed is CCDC86; the disease is diffuse large B-cell lymphoma.