By using this stringent cut-off, 6 factors expressed predominantly in brain (MECP2, STMN2), lung (H2AFY, NUMA1), and testis (CYCLON, LYAR), were identified as showing abnormally high expression in the index DLBCL cell line (Table 1 and Fig 1B). The gene discussed is LYAR; the disease is diffuse large B-cell lymphoma.