CEBPA and chronic obstructive pulmonary disease: A recent report further substantiated the role of C/EBP transcription factors in the process of squamous metaplasia of the lung, as mice with a conditional deletion of C/EBPα in the lung developed squamous metaplasia in adulthood, together with other features of chronic obstructive pulmonary disease, COPD, although no p63 connection was mentioned (Didon et al, 2010).