NR2E3 and atrial fibrillation: Fig. 1A,B show the cilioretinal flatmounts of P21 wild-type (WT; A) and P19 rd7 (B) mice. Fig. 1C shows examples of AF spots (arrows) and rosettes (circular halos). Although the number of retinal rosettes increased from P14 to P21, the number of rosettes decreased progressively from P21 through to P720. In contrast, AF spots that were absent at P14 were first detected as early as P21 (Fig. 1G), and the number increased gradually with age (Fig. 1F–K).