In a mouse model of Huntington’s disease (HD), intrastriatally transplanted BM-MSCs integrated in the host brain and exerted neurotrophic effects that correlate with increased levels of laminin, von Willebrand factor (VWF), stromal cell-derived factor-1 (SDF-1) α, and the SDF-1 receptor CXCR4, which in turn enhanced angiogenesis in the damaged striatum [44]. This evidence concerns the gene LAMB2 and Huntington disease.