A more recent study analyzing the function of EZH2 in breast and prostate cancer lines has reported that the recruitment of EZH2 and Suz12 (both PRC2 subunits) to the promoter region of the tumor-suppressor gene RKIP is accompanied by H3K27 and H3K9 trimethylation [19]. This evidence concerns the gene EZH2 and Familial prostate cancer.