In addition, in two experiments (n = 10 mice/treatment) the effect of vitamin D deficiency on BALF granulocyte numbers in male mice was overcome by sequential challenges with OVA (3 daily doses), which enhanced eosinophil numbers in BALF (>100-fold, Fig. 1B; Fig. 3), but had little effect on BALF IL-5 levels (Fig. 1C; Fig. 3). The gene discussed is IL5; the disease is vitamin D deficiency.