Following our previous studies on FMOD[2] and ROR1[8] in CLL, both located on chromosome 1, the present study was undertaken to explore the gene and protein expression of PRELP in CLL and other hematological malignancies, in our endeavour to explore uniquely expressed molecules in CLL which may play a role in the pathobiology of the disease. Here, FMOD is linked to B-cell chronic lymphocytic leukemia.