Among the PKCδ-regulated genes in prostate cancer cells, we identified FOSL1, BCL2A1, SERPINB2, and TRAF1. Both FOSL1 and BCL2A1 were found to be mediators of phorbol ester- and etoposide-induced apoptosis in LNCaP prostate cancer cells [15]. The gene discussed is SERPINB2; the disease is prostate carcinoma.