The most significant KEGG pathway based on global EVI1 binding were Pathways in cancer (p = 2.5E−15), followed by Jak-Stat signaling (p = 2.3E−11), Mapk signaling (p = 9.1E−9) and Chemokine signaling (p = 1.6E−7). The gene discussed is MECOM; the disease is cancer.