MECOM and acute myeloid leukemia: Direct EVI1 target genes were also significantly enriched for KEGG pathways specific for Acute Myeloid Leukemia (p = 5.4E−6), Apoptosis (p = 3.9E−4), Hematopoietic Cell Lineage (p = 3.5E−5) and p53 signaling (p = 2.1E−3 ).