Among the differentially expressed genes, there were 29 transcripts which were shared between B cells and CD4+ T cells (Figure 2, far right panel); of these, 28 transcripts had a ≥2 fold change in active SLE CD4+ T cells and 12 transcripts had a ≥2 fold change in the inactive SLE CD4+ T cells. The gene discussed is CD4; the disease is systemic lupus erythematosus.