The shared transcripts were mostly well-known IFN-inducible transcripts including IRF7, MX1 and STAT1. As shown in the Venn diagram (Figure 4) a majority of highly expressed SLE transcripts were unique for either B cell or myeloid cell subsets, whereas approximately half of the CD4+ T cell transcripts were shared with the other subsets. The gene discussed is IRF7; the disease is systemic lupus erythematosus.