Adjustment for putative confounders (age, gender, BMI, hypertension, smoking, diabetes, hypercholesterolemia) attenuated the OR for the normalized ETP to 2.4 (95% CI 1.3–4.5) and enhanced the OR for the normalized peak height to 2.6 (95% CI 1.3–5.0), both assessed with the 1 pM TF trigger. The gene discussed is TF; the disease is familial hypercholesterolemia.