ACE and Stroke: It is worthwhile for future DRVs studies to incorporate alternate DRPs as sources of laboratory and physiologic abnormalities as these can occur from problems with medication adherence (e.g. low INR reported in anticoagulated patient admitted for stroke); drug interaction (e.g. subtherapeutic phenytoin value reported in patient receiving concomitant antibiotic and admitted with seizure); or inappropriate prescribing (e.g. increasing ACE inhibitor dose in the face of hyperkalemia) [55].