INS and cancer: By considering the genetic pathways listed in KEGG as being involved in cancer development, we identified several significantly related pathways, including MAPK signaling, neurotrophin signaling, TGF-beta signaling, Wnt signaling, insulin signaling, p53 signaling, ErbB signaling, Notch signaling, chemokine signaling, Jak-STAT signaling, T cell receptor signaling, calcium signaling, RIG-I-like receptor signaling, mTOR signaling, and GnRH signaling (Figure 4, Table S6).