CD8A and neoplasm: DCs from HLA-A*02 donors loaded with PNY were capable of inducing, ex vivo, CD8+ T-cells specific to NY157-165 MHC class I-restricted epitopes, indicating that intracellular PNY traffic leads to the MHC I loading compartment where whole antigen processing generates the same antigenic peptides as are presented at the surface of tumor cells.