In this way, one can find protein TDP-43, mutant proteins, small interfering RNA, are close to DNA-binding proteins and nuclear proteins, microRNAs related to 3′ untranslated regions, DMD protein near to dystrophin, MGMT protein and IDH1 protein quite close to a group of major substances acting as regulators and markers in the biological process of cancer. This evidence concerns the gene MGMT and cancer.