Plasma FGF23 concentration was not different in the patients with the viral or non-viral etiology of the liver disease (LnFGF23 mean ± SD: 5.44±1.45 viral hepatitis −; 5.70±1.42 viral hepatitis +; p = 0.21) but was significantly higher in patients with history of refractory ascites (LnFGF23 mean ± SD: 5.16±1.32 refractory ascites −; 6.40±1.37 refractory ascites +; p<0.001). The gene discussed is FGF23; the disease is liver disorder.