Ceruloplasmin has been found to be upregulated in the retina in multiple pathological conditions including light damage, optic nerve crush, glaucoma, and diabetes (Levin and Geszvain, 1998; Chen et al., 2003; Miyahara et al., 2003; Farkas et al., 2004; Gerhardinger et al., 2005). This evidence concerns the gene CP and glaucoma.