All variables that were significantly related to liver fibrosis (Ang1, Ang2, Ang2/Ang1, age, AST, ALT, GGT, platelet count, INR, albumin, and bilirubin) were analyzed together by step-backward multiple regression, wherein Ang2, age, platelet count, INR, AST, and GGT were associated independently with liver fibrosis (Table 2). This evidence concerns the gene ANGPT1 and Hepatic fibrosis.