High amylose starches have potential of controlling high-fat diet-induced obesity by modulating hepatic fatty acid oxidation [40] while RS induces increase in the levels of anti-diabetic hormones i.e., glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) [41, 42]. This evidence concerns the gene PYY and obesity due to melanocortin 4 receptor deficiency.