The major causes of diabetes includes either complete absence of insulin hormone (Type I) due to auto-immune disorder/genetic defects/ abnormal physiology (unknown causes) or inadequate biological response towards insulin (Type II) due to down-regulation of receptors (usually in adults due to obesity or other lifestyle factors) [28–30], leading to elevated blood glucose levels [24]. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.