Genes that are upregulated in sarcoma include MUC4, CD24, FOXL1, ANGPTL2, HIF1a, MDK, cMET, TIMP-2, PRL, PCSK1, IGFR-1, TIE1, KDR, TEK, FLT1 and several microRNAs. This evidence concerns the gene KDR and sarcoma.