WFDC2 and neoplasm: Different types of proteins other than commonly accepted and used tumor marker - CA125 (carbohydrate antigen 125) [7-9] or a new biomarker - HE4 (human epididymis protein 4) [9,10] such as cytokines (M-CSF, IL-6) [11-14], and metalloproteinases are currently investigated [15-17].