In an investigation to clarify whether the T-helper (Th)1/Th2 imbalance is involved only in the coronary arteries inflammation or also in the myocardial inflammation and also to explore the importance of the imbalance of Th1/Th2 in the AMI, Cheng and colleagues (2005) observed that IFN-gamma-producing T cells were significantly increased in patients with AMI and unstable angina within 24 hours after the onset of symptoms. The gene discussed is IFNG; the disease is angina pectoris.