The incremental AUC above 0.5 over the base model was slightly, but significantly increased by 2.3% from the AUC of the base model in the additional model of ALT (P = 0.02), which was the best marker for diabetes prediction in the single model with men excluding the model of glycaemic biomarkers, and 0.2% in the model with BMI (not significant), which was the best such marker in women. The gene discussed is GPT; the disease is diabetes mellitus.