HSPA5 and colorectal carcinoma: Of the estimated allele ORs of 1.38 and 1.60, our study with 414 CRC cases and 502 matched controls provided the statistical power of 0.80 and 0.95 at the nominal type I error rate of 0.05, respectively, indicating that our samples could provide adequate power in identifying the association of the risk of CRC with the two GRP78 polymorphisms.