PPARG and obesity due to melanocortin 4 receptor deficiency: To investigate the possible molecular mechanism of wCL on the suppression of obesity, the levels of CCAAT/enhancer binding protein α (CEBPα) mRNA and peroxisome proliferator-activated receptor γ (PPARγ) mRNA were monitored in 3T3-L1 cells treated with increasing concentrations of wCL.