Parkinson's disease and PPS caused by mutations in mitochondrial proteins parkin[40▪▪,83–88,89▪,90▪], PINK1[40▪▪,91], PLA2G6[35▪] and C19orf12[33,34▪▪], respectively, frequently have Lewy-body pathology. The gene discussed is PLA2G6; the disease is popliteal pterygium syndrome.