Aggressive NK-cell neoplasms are almost always associated to Epstein Barr Virus(EBV) and similarly to that occurring in Hodgkin’s lymphoma andnasopharyngeal carcinoma, the neoplastic NK-cells usually have a type II latencypattern, expression of EBV nuclear antigens (EBNA) and latent membrane proteins(LMP) being limited to EBNA-1, LMP-1, and LMP-2 [31]. Here, PDLIM7 is linked to carcinoma.